Mechanical Engineer III (Early RD)

Company: Tailored Management
Location: Santa Clara
Posted on: February 10, 2026

Job Description:

Job Title: - Mechanical Engineer III (Early R&D) Location - 2881 Scott Blvd, Santa Clara, CA 95050 Duration: 6-month contract (with potential extension or conversion) Pay Rate: $48.00 $90.13/hour (W2) Work Model: Onsite Benefits - Weekly pay, Medical, Dental, Vision Interview Process Phone interview In-person interview (candidate must present a bio/technical presentation outlining skill sets and experience) Company Overview At Roche, we are driven by a mission to create a healthier future. We continuously innovate to advance science and ensure access to healthcare for today and future generations. Roche Sequencing Solutions is focused on making next-generation sequencing (NGS) simple, scalable, and accessible through highly integrated, end-to-end solutions. Our Systems Technology Group is responsible for developing cutting-edge technologies that enhance DNA sequencing workflows. We are seeking a Principal Mechanical Engineer to lead the mechanical design and development of next-generation sequencing instrumentation. Role Summary This is a hands-on, senior-level engineering role for a multidisciplinary expert focused on solving complex mechanical challenges within advanced sequencing systems. The role involves concepting, designing, building, testing, and integrating electro-mechanical, pneumatic, thermal, and fluidic systems to ensure performance, reliability, and scalability. Core Responsibilities Lead end-to-end mechanical design and development of electro-mechanical, pneumatic, fluidic, and thermal sub-systems Collaborate with cross-functional teams (electrical, consumables, materials) to define and manage critical technical interfaces Design mechanisms for automated reagent and flow cell loading, clamping, and sealing with high reliability Architect and implement thermal control systems, including heating/cooling elements, sensors, condensation control, and heat management Partner with simulation experts to guide and validate CFD, thermal, and optical models using empirical data Serve as the technical owner for assigned sub-systems during integration, verification, and troubleshooting Lead cross-functional design reviews and resolve technical trade-offs Manage technical execution, timelines, and deliverables for assigned sub-systems Create and maintain design documentation including CAD models, drawings, and specifications Contribute to system-level technical strategy and architecture decisions Present technical progress, data, and design trade-offs to stakeholders Required Qualifications Education & Experience: PhD with 5 years of industry experience OR Masters degree with 10 years of industry experience OR Bachelors degree with 10 years of industry experience (Mechanical Engineering, Bioengineering, or related field) Proven hands-on expertise designing and testing complex mechanical, electro-mechanical, and pneumatic systems (life sciences/diagnostics preferred) Strong experience in thermal management and precision temperature control systems Experience designing fluidics systems (pumps, valves, tubing, sensors, materials) Proficiency in 3D CAD tools (e.g., SolidWorks) and manufacturing drawings Experience with machining, injection molding, and additive manufacturing Strong troubleshooting skills across hardware, software, and chemistry interfaces Proficiency with machine shop tools, test equipment, and rapid prototyping technologies Experience using Python, LabVIEW, or similar tools for device control and data acquisition Preferred Qualifications Experience leading technical projects and mentoring junior engineers Proficiency with simulation tools (CFD, FEA) Experience developing NGS or genomics instrumentation Background in regulated product development environments Strong communication skills with both technical and non-technical stakeholders Excellent organizational and multitasking skills in fast-paced environments TMN

Keywords: Tailored Management, Oakland , Mechanical Engineer III (Early RD), Engineering , Santa Clara, California