OaklandRecruiter Since 2001
the smart solution for Oakland jobs

Downstream Process Development Scientist

Company: Bevov
Location: Oakland
Posted on: October 17, 2020

Job Description:

Position Overview We're looking for an excellent Downstream and Purification Process Development Scientist to join our client's dynamic team in South San Francisco. This role is an exciting opportunity to lead the development of formulations for building novel exosome therapeutics. Responsibilities Lead downstream purification process development for exosome therapeutic development programs, currently in the preclinical stage.

Develop FPLC-based scalable column chromatographic methods for the purification and isolation of high-quality exosome products, including, but not limited to, preparatory scale affinity purification, ion exchange (IEX) chromatography, multimodal, hydrophobic interaction, and size exclusion (SEC) chromatography.

Execute and improve current Tangential Flow Filtration (TFF) procedure for isolation and formulation of exosome products.

As a subject matter expert, maintain knowledge and implement state-of-the-art technologies and processes for exosome purification and isolation.

Author process descriptions, SOPs, protocols, and tech transfer documents necessary for seamless process transfer to internal or external collaborators.

Meticulously maintain complete and accurate records of all work performed in LIMS and/or electronic lab notebook (ELN).

Play a central role in selection and interaction with contract manufacturers/research organizations, key suppliers, and other external vendors. Prior experience working with and managing CMO/CDMO/CRO desired.

Manage the downstream process development function, including operational considerations, lab buildout and equipment purchases, team recruitment, and training, setting key metrics and objectives, and providing guidance and mentorship to junior staff.

Coordinate tasks across multiple projects, demonstrating prioritization and planning. We are a start-up and are looking for applicants who are ready and willing to ‘roll their sleeves up’ and be the Key Driver to meet project timelines and milestones.

Qualification and Skills BS/MS degree with 6+ experience or Ph.D. degree with 3+ years of experience in a drug development setting.

4+ years of biologics downstream process development experience using a FPLC system (e.g. AKTA)

Expertise in method/protocol development and scale-up for biologics purification, including, but not limited to affinity, cation exchange (CEX), anion exchange (AEX), viral filtration, and tangential flow filtration (TFF) is required.

Familiarity with HPLC based analytical methods (SEC, RP-HPLC, ion-exchange, hydrophobic interaction chromatography, etc)

Prior experience with IND regulatory requirements, GMP environments, and quality documentation is highly desired.

Demonstrated ability to work independently with minimal supervision.

Familiarity with Design of Experiment (DOE) and comfortable working with analytical tools to create high-quality unbiased analyses.

Prior experience with a successful technology and process transfers to third party vendors (CRO/CDMO/CMO) is highly desired.

Experience mentoring, coaching, and training junior staff members are preferred.

Excellent interpersonal skills, including clear, succinct, and timely communication and proven ability to foster strong relationships with other team members and stakeholders.

Highly self-motivated and detail-oriented, with proven ability to work in a dynamic, fast-moving team.

Comfortable working with a data-driven team and collaborating with research scientists, data scientists, and platform engineers.

Familiarity or experience with scripting and statistical analysis of your data.

Experience collaborating with computational scientists while analyzing your data.

Keywords: Bevov, Oakland , Downstream Process Development Scientist, Other , Oakland, California

Click here to apply!

Didn't find what you're looking for? Search again!

I'm looking for
in category
within


Other Other Jobs


Full-Stack Software Engineer - Woodland, CA
Description: Job DescriptionJoin Hired and find your dream job as a Full Stack Software Engineer at one of 10,000 companies looking for candidates just like you. Companies on Hired apply to you, not the other way (more...)
Company: Hired
Location: Woodland
Posted on: 10/27/2020

Grocery Pick-up Driver
Description: Job Description Shipt is a same-day delivery service that helps people get the things they need, like fresh produce and household essentials, from stores they trust. Help people save time and have fun (more...)
Company: Shipt
Location: Woodland
Posted on: 10/27/2020

CDL-A Truck Drivers - Dedicated Account - Immediate Placement!
Description: Job Description Dedicated Truck Driver Jobs Hiring CDL-A Truck Drivers for our Dedicated Jobs Refrigerated Trucking is one of the safest bets in the trucking industry
Company: C.R. England
Location: Woodland
Posted on: 10/27/2020


Truck Driver - Average $60,000/Year - Great Benefits + No-Touch
Description: The SYGMA Network is now hiring CDL Class A Drivers for Linehaul Routes in Illinois Every day, the country's most successful restaurant chains rely on The SYGMA Network to supply everything from fresh
Company: SYGMA - Illinois - Linehaul Drivers
Location: Woodland
Posted on: 10/27/2020

Shopper Team Member - flexible hours
Description: Job Description Shipt is a membership-based marketplace that helps people get the things they need, like fresh produce and household essentials, from stores they trust. Help people save time and have (more...)
Company: Shipt
Location: Woodland
Posted on: 10/27/2020

Deliver with Uber Eats this Fall
Description: Deliver with Uber Eats this Fall Woodland, CA 2854 C2-720068 Deliver with Uber. Earn on your schedule. Deliver with Uber Eats on your schedule. Deliver for a few hours in the mornings, every night, or (more...)
Company: Uber Eats
Location: Woodland
Posted on: 10/27/2020

Shipt Worker - Shopper & Delivery Driver
Description: Job Description Help people get what they need while earning extra income. Shipt is a marketplace that provides fresh produce, household essentials, and more from trusted local stores. There's never (more...)
Company: Shipt
Location: Woodland
Posted on: 10/27/2020

Optical Assistant
Description: Optician/Optical Assistant Small private Optometry practice seeking FT optician/optical assistant. Must
Company: Liebowitz & Brown
Location: Woodland
Posted on: 10/27/2020

Front-End Engineer - Woodland, CA
Description: Job DescriptionJoin Hired and find your dream job as a Front-End Engineer at one of 10,000 companies looking for candidates just like you. Companies on Hired apply to you, not the other way around. You'll (more...)
Company: Hired
Location: Woodland
Posted on: 10/27/2020

Shop and deliver groceries on your own schedule
Description: Job Description Shipt is a membership-based marketplace that helps people get the things they need, like fresh produce and household essentials, from stores they trust. Help people save time and have (more...)
Company: Shipt
Location: Woodland
Posted on: 10/27/2020

Log In or Create An Account

Get the latest California jobs by following @recnetCA on Twitter!

Oakland RSS job feeds